Autonomic/CV Drugs — Flashcards

Flashcard 1431: Hydroxyurea is useful in the treatment of sickle cell anemia because it increases levels of _____ to > 15%.

Answer: HbF

Flashcard 1432: Electrolyte abnormalities due to succinylcholine can lead to a life-threatening _____

Answer: cardiac arrhythmia

Flashcard 1433: Dual antiplatelet therapy (DAPT) with _____ and _____ is used to prevent coronary stent thrombosis.

Answer: aspirin

Extra: Dual antiplatelet therapy (DAPT) typically consists of aspirin and a P2Y12 inhibitor (like clopidogrel, prasugrel, or ticagrelor). The suffix "-grel" is a common mnemonic for many drugs in this class. DAPT is required post-stent placement to prevent acute and subacute stent thrombosis.

Flashcard 1434: Canagliflozin, dapagliflozin, and empagliflozin are all examples of _____ inhibitors

Answer: SGLT2

Flashcard 1435: Raloxifene is a SERM that acts as an estrogen receptor _____ in breast and _____ in endometrium

Answer: antagonist

Flashcard 1436: Are prednisone and indomethacin used in combination in the treatment of an acute gout attack? _____

Answer: No

Flashcard 1437: What is the contraindication for Prostaglandin F2alpha (hemabate) in postpartum hemorrhage? _____

Answer: Asthma

Flashcard 1438: What is first-line treatment for vasomotor rhinitis? _____

Answer: Intranasal antihistamines (e.g. azelastine) Intranasal glucocorticoids (e.g. fluticasone)

Flashcard 1439: Metformin (biguanides) = _____ liver gluconeogenesis (main MOA) and _____ insulin sensitivity

Answer: ↓

Flashcard 1440: Digitalis can increase heart rate due to _____ of the atria or ventricles

Answer: ectopy