Antimicrobials — Flashcards

Mycophenolate mofetil is a powerful inhibitor of _____ proliferation (cell type)

Rituximab binds CD20 of B-cells and tags it for natural killer cells via antibody-_____ cytotoxicity

Which antitumor monoclonal antibody targets HER2 (c-erbB2)?_____

Which antitumor monoclonal antibody is used to treat stage IV colorectal carcinoma (wild-type KRAS)?_____

What toxic intermediate is formed in small amounts by metabolism of acetaminophen? _____

Phase _____ of clinical trials uses a large number of patients randomly assigned either to a treatment under investigation or the best available treatment (or placebo)

Rituximab can lead to a depletion of what antibody type? _____

What formula is used to calculate maintenance dose? _____

Ipilimumab is a checkpoint inhibitor that binds to _____ on T cells.

Fomepizole works as an antidote for methanol/ethylene glycol poisoning by inhibiting _____