Antimicrobials — Flashcards

Rituximab binds CD20 of B-cells and tags it for natural killer cells via antibody-_____ cytotoxicity

Which antitumor monoclonal antibody targets HER2 (c-erbB2)?_____

What toxic intermediate is formed in small amounts by metabolism of acetaminophen? _____

Cladribine is a DNA polymerase inhibitor that treats _____ leukemia

Fomepizole works as an antidote for methanol/ethylene glycol poisoning by inhibiting _____

Which antitumor monoclonal antibody is used to treat stage IV colorectal carcinoma (wild-type KRAS)?_____

What is the most serious adverse effect associated with lamotrigine use?_____

Rituximab can lead to a depletion of what antibody type? _____

5-fluorouracil can be used topically to treat _____

In _____ order kinetics, the rate of reaction is directly proportional to the substrate (drug) concentration