Antimicrobials — Flashcards

Eculizumab is a monoclonal antibody for the _____ complement protein

_____ inhibits the enzyme dihydroorotate dehydrogenase, which catalyzes the conversion of dihydroorotate to orotic acid (de novo pyrimidine synthesis).

What is the treatment for overdose of drugs that act as weak acids (e.g. phenobarbital, methotrexate, aspirin)?_____

Adalimumab is a monoclonal antibody against _____

In _____ order kinetics, the rate of reaction is directly proportional to the substrate (drug) concentration

Neutropenia may result from drug toxicity, especially _____

What toxic intermediate is formed in small amounts by metabolism of acetaminophen? _____

5-fluorouracil can be used topically to treat _____

Cladribine is a DNA polymerase inhibitor that treats _____ leukemia

Which antitumor monoclonal antibody targets HER2 (c-erbB2)?_____