Antimicrobials — Flashcards

Flashcard 311: What can be used in H. pylori triple therapy for those with a penicillin allergy? _____

Answer: Metronidazole

Flashcard 312: Oral isotretinoin (vitamin A) is used to treat severe cystic _____

Answer: acne

Flashcard 313: Cytarabine can result in _____ with increased risk for infection

Answer: immunosuppression

Flashcard 314: Stevens-Johnson syndrome typically arises as an adverse _____ reaction

Answer: drug

Extra: Toxic epidermal necrolysis/Stevens-Johnson syndrome This 6-month-old patient presents with toxic epidermal necrolysis, the severe form of Stevens-Johnson syndrome. Smallpox vaccination can trigger toxic epidermal necrolysis. Stevens-Johnson syndrome following sulfonamide treatment Blistering of skin and epidermal detachment involving the conjunctiva are visible, resembling a superficial burn.

Flashcard 315: Because the oral mucosa contains rapidly dividing cells, patients taking bleomycin/anthracyclines can experience _____ and _____

Answer: mucositis

Flashcard 316: Which commonly used disinfectant causes halogenation of proteins and nucleic acids? _____

Answer: Iodine

Flashcard 317: What enzyme is inhibited by Methotrexate? _____

Answer: Dihydrofolate reductase (eukaryotic)

Flashcard 318: Eteplirsen is an antisense drug used to treat _____ by allowing the generation of a partially functional _____ protein

Answer: Duchenne Muscular Dystrophy

Flashcard 319: Anthracyclines (doxorubicin, daunorubicin) form _____ which cause breaks in _____

Answer: free radicals

Flashcard 320: Rituximab and Cetuximab are _____ monoclonal antibodies

Answer: Chimeric