Antimicrobials — Flashcards

Flashcard 301: Rituximab is an antitumor monoclonal antibody that targets _____ of B-cells

Answer: CD20

Flashcard 302: What type of anemia results from methotrexate use? _____

Answer: Megaloblastic (macrocytic) anemia

Flashcard 303: Nitrosureas are chemotherapeutics which can be recognized by the suffixes _____ and -zotocin

Answer: -mustine

Extra: Nitrosureas are lipophilic alkylating agents that cross the blood-brain barrier. They are primarily used to treat brain tumors (e.g., glioblastoma multiforme). Unlike other nitrosureas, streptozocin is relatively less lipophilic and is used for insulinomas.

Flashcard 304: 6-mercaptopurine is used to treat _____ malignancies

Answer: hematologic (e.g. ALL)

Flashcard 305: What drugs should be used to treat Toxoplasmosis? _____

Answer: Pyrimethamine/sulfadiazine

Flashcard 306: Cystinuria may be treated with _____ agents, such as penicillamine

Answer: chelating

Flashcard 307: What drug treats the dormant hypnozoites of P. vivax and P. ovale? _____

Answer: Primaquine

Flashcard 308: What can be used in H. pylori triple therapy for those with a penicillin allergy? _____

Answer: Metronidazole

Flashcard 309: Oral isotretinoin (vitamin A) is used to treat severe cystic _____

Answer: acne

Flashcard 310: Etoposide and teniposide can result in _____

Answer: alopecia