Antimicrobials — Flashcards

Nowadays, patients typically can get chronically exposed to Arsenic in a couple of different situations, including: (1) - _____ smoke (2) - Herbicides used in vineyards (3) - metal smelting

Ustekinumab is a monoclonal antibody against _____ used to treat psoriasis/psoriatic arthritis

Rituximab can be used to treat _____ leukemia

Tyrosine Kinase inhibitors work by targeting downstream signaling pathways involved in growth - the most important being: - _____ leads to increased Bcl-2 expression (anti-apoptosis) - JAK/STAT which would've led to increased cell proliferation - Ras/MAPK which would've led to increased cell growth - Src/FAK which would've led to increased cell motility (invasion) and decreased cell adhesion (migration)

Upon bioactivation, 5FU (now 5-FdUMP) covalently complexes with _____ and folic acid, reducing DNA synthesis

Which aminoglycoside is a GI intraluminal agent active against parasites? _____

Which calcineurin inhibitor binds to FK506 binding protein (FKBP)? _____

Prior to a bone marrow transplant, Busulfan can be used as a(n) _____ agent

Which phase of the cell cycle does methotrexate act at? _____

Imatinib specifically inhibits the Bcr-Abl fusion protein by blocking the _____ portion