Neoplasia — Flashcards

Flashcard 241: Chondrosarcomas, Ewing sarcomas, and Osteosarcomas commonly metastasize to which location? _____

Answer: Lungs (hematogenously)

Flashcard 242: Which virus is strongly associated with the mixed cellularity and lymphocyte depleted subtype of Hodgkin’s lymphoma? _____

Answer: Epstein-Barr Virus

Flashcard 243: Cutaneous _____ is a malignant tumor associated with chronic lymphedema

Answer: angiosarcoma

Extra: Angiosarcoma is a malignant tumor of vascular endothelial cells. Stewart-Treves syndrome refers specifically to cutaneous angiosarcoma arising in the setting of chronic lymphedema.

Flashcard 244: Positive TRAP stain for diagnosis of hairy cell leukemia has been largely replaced with _____

Answer: flow cytometry

Extra: Atlas: Other:

Flashcard 245: Is Warthin tumor typically a benign or malignant salivary gland tumor? _____

Answer: Benign

Extra: Warthin tumor (papillary cystadenoma lymphomatosum) is a benign cystic tumor with germinal centers. It is strongly associated with smoking.

Flashcard 246: Which carcinogen is associated with the following types of cancer? _____ Squamous Cell Carcinoma of Oropharynx and Upper Esophagus Pancreatic Carcinoma Hepatocellular Carcinoma

Answer: Ethanol

Flashcard 247: Carcinogens are agents that damage cellular _____ of stem cells

Answer: DNA

Flashcard 248: Renal cell carcinoma often originates from the _____ cells of the nephron

Answer: PCT

Extra: Atlas:

Flashcard 249: CML is distinguished from a leukemoid reaction (benign neutrophilia) by a(n) negative _____ stain

Answer: leukocyte alkaline phosphatase (LAP)

Extra: Other: helps distinguish CML from leukemoid reaction (high LAP)

Flashcard 250: The _____ is a unique site of distant metastasis from lung cancer

Answer: adrenal gland