Neoplasia — Flashcards

_____ process is a pathologic process that replaces bone marrow (e.g. metastatic cancer)

Do both alleles of a tumor suppressor gene need to be mutated in order for expression of disease?_____

In invasive carcinoma, cell-cell contacts are lost by inactivation of _____

Follicular lymphoma is distinguished from reactive follicular hyperplasia by _____ of normal lymph node architecture

In the _____ pathway (25%) of endometrial carcinoma, the carcinoma arises in an atrophic endometrium with no precursor lesion

In patients with leukemia, unregulated growth and differentiation of WBCs in bone marrow results in _____

HPV-related vulvar carcinoma arises from _____, a dysplastic precursor lesion characterized by koilocytic change, disordered cellular maturation, nuclear atypia, and increased mitotic activity

Laryngeal papillomas may have _____ change on biopsy

Small (oat) cell carcinoma is _____ located

Which subtype of Hodgkin lymphoma is usually seen (strongest association) in the elderly and HIV+ individuals? _____