Neoplasia — Flashcards

HPV-related vulvar carcinoma arises from _____, a dysplastic precursor lesion characterized by koilocytic change, disordered cellular maturation, nuclear atypia, and increased mitotic activity

What pathology is characterized by a deficiency of the enzymes used in mismatch base repair? _____

Gross examination of _____ shows multiple, well-defined, white, whorled masses that may distort the uterus and impinge on pelvic structures

Do both alleles of a tumor suppressor gene need to be mutated in order for expression of disease?_____

What three genetic alterations are commonly associated with papillary thyroid carcinoma?

Does the radial phase of melanoma growth have a high risk of metastasis? _____

_____ thyroid carcinoma is due to PAX8-PPAR mutations.

In the _____ pathway (25%) of endometrial carcinoma, the carcinoma arises in an atrophic endometrium with no precursor lesion

Agents that damage DNA are known as _____

Laryngeal papillomas may have _____ change on biopsy