Central Nervous System Pharmacology — Flashcards

Opiate receptor activation causes closure of _____-synaptic Ca2+ channels, which decreases release of neurotransmitters (e.g. ACh, NE, 5-HT, glutamate, substance P)

First Aid Pharmacology: _____ and phenytoin are first-line agents for treatment of tonic-clonic seizures

Side effects of metoclopramide include _____ and depression as a result of central D2 blockade

Phencyclidine (PCP) is a hallucinogen that works primarily as an _____ receptor antagonist

Cocaine exerts its effects via inhibition of the _____ and DAT transporters (reuptake inhibitor)

Effect of acute ethanol is inhibitory on _____ receptor channels and voltage-gated Ca2+ channels

_____ works in the Renshaw cells of the spinal cord

Hint: which exotoxin

_____ is a histamine H3-receptor antagonist/inverse agonist indicated for the treatment of narcolepsy with or without cataplexy.

Huntington disease may be treated with _____ or reserpine, which inhibit VMAT, decreasing dopamine vesicle packaging and release

Neuro/Psych _____ is a non-ergot D3 receptor agonist that is used in initial treatment of Parkinson disease