Endocrinology — Flashcards

Flashcard 191: _____ is the most common endocrinopathy occurring as a paraneoplastic syndrome.

Answer: Hypercalcemia (Humoral hypercalcemia of malignancy)

Extra: Hypercalcemia is the most common paraneoplastic syndrome overall, typically mediated by PTHrP (Parathyroid Hormone-related Protein). SIADH is the most common paraneoplastic syndrome specifically associated with Small Cell Lung Cancer (SCLC). Cushing syndrome (ectopic ACTH) is also a classic paraneoplastic syndrome but is less common than hypercalcemia and SIADH.

Flashcard 192: _____ test can be used to confirm the diagnosis of Primary Hyperaldosteronism

Answer: Saline infusion

Flashcard 193: What is the most common manifestation of primary hyperaldosteronism?_____

Answer: Hypertension

Flashcard 194: Amongst autoimmune diseases, the strongest association of vitiligo is with _____

Answer: thyroid disorders

Flashcard 195: What type of endemic cretinism is associated with an euthyroid state and goitre?_____

Answer: Neurological

Flashcard 196: An adrenal mass should never be biopsied until the _____ has been biochemically excluded

Answer: pheochromocytoma

Flashcard 197: _____ is the most common cause of hypercalcemia detected incidentally.

Answer: Hyperparathyroidism

Flashcard 198: The investigation of choice for insulinoma is the determination of _____-hour fasting glucose and serum _____ levels.

Answer: 72; insulin

Flashcard 199: _____ phenomenon is characterized by _____thyroidism due to _____ thyroid hormone production following the administration of contrast agents

Answer: Jod-Basedow; hyper; enhanced

Flashcard 200: _____ is the most common hormone that is affected in the case of Sheehan syndrome.

Answer: Growth hormone (GH)