Lipid Disorders — Flashcards

Flashcard 1: Hypothyroidism presents with _____ because thyroid hormone normally increases the expression of LDL receptors.

Answer: hypercholesterolemia

Extra: Thyroid hormone normally increases the expression of LDL receptors on hepatocytes, which facilitates the clearance of LDL from the circulation. In hypothyroidism, the decreased expression of these receptors leads to reduced LDL clearance and subsequent hypercholesterolemia.

Flashcard 2: Hyperthyroidism presents with _____ due to increased expression of LDL receptors on hepatocytes.

Answer: hypocholesterolemia

Flashcard 3: Metabolic syndrome presents with _____uricemia

Answer: hyper

Flashcard 4: What is the treatment of choice for De Quervain's Thyroiditis?_____

Answer: NSAIDs

Flashcard 5: _____ phenomenon occurs due to excess night-time dose of insulin

Answer: Somogyi

Flashcard 6: Secondary sexual characteristics are normal in _____ and Androgen Insensitivity Syndrome (AIS).

Answer: Müllerian agenesis (MRKH)

Flashcard 7: Summary of laboratory findings in parathyroid diseases (PTH, Calcium, Phosphate)

Answer: See table for Primary/Secondary/Tertiary Hyperparathyroidism, Hypoparathyroidism, and Pseudohypoparathyroidism.

Extra: • **Primary Hyperparathyroidism**: ↑ PTH, ↑ Ca²⁺, ↓ PO₄³⁻ • **Secondary Hyperparathyroidism**: ↑ PTH, ↓ Ca²⁺, ↑ PO₄³⁻ • **Hypoparathyroidism**: ↓ PTH, ↓ Ca²⁺, ↑ PO₄³⁻ • **Pseudohypoparathyroidism**: ↑ PTH, ↓ Ca²⁺, ↑ PO₄³⁻ (End-organ resistance)

Flashcard 8: 1. Identify → _____ 2. Use → _____

Answer: Insulin Syringe

Extra: y

Flashcard 9: Features of MEN 4 include (similar to MEN 1): Parathyroid adenoma, Pituitary adenoma, _____ tumors and Adrenal + renal tumors

Answer: Reproductive organ

Flashcard 10: _____ diabetes insipidus is characterized by polyuria and polydipsia with an inability to concentrate urine due to lack of ADH

Answer: Central