Thyroid Disorders — Flashcards

Flashcard 1: Which two antibodies are associated with Hashimoto thyroiditis? _____ and anti-thyroid peroxidase (anti-microsomal)

Answer: Anti-thyroglobulin

Flashcard 2: Most commonly, patients with euthyroid sick syndrome will have:- serum TSH _____- total serum T4 normal- total serum T3 decreased- reverse T3 increased

Answer: normal

Flashcard 3: Sign of _____: loss of hair in the outer third of eyebrows: seen in Hypothyroidism

Answer: Hertoghe

Flashcard 4: Subacute granulomatous thyroiditis (de Quervain) may initially present with _____, which typically is followed by a brief hypothyroid state

Answer: hyperthyroidism

Flashcard 5: What is the treatment of choice for De Quervain's Thyroiditis?_____

Answer: NSAIDs

Flashcard 6: What HLA subtypes are associated with Hashimoto thyroiditis? _____ and DR5

Answer: DR3

Flashcard 7: Patients with _____ may develop hypoventilation from respiratory muscle weakness

Answer: hypothyroidism

Flashcard 8: What is the first investigation to be done in a patient with a clinically apparent thyroid swelling?_____

Answer: TFT

Flashcard 9: Secondary sexual characteristics are normal in _____ and Androgen Insensitivity Syndrome (AIS).

Answer: Müllerian agenesis (MRKH)

Flashcard 10: Summary of laboratory findings in parathyroid diseases (PTH, Calcium, Phosphate)

Answer: See table for Primary/Secondary/Tertiary Hyperparathyroidism, Hypoparathyroidism, and Pseudohypoparathyroidism.

Extra: • **Primary Hyperparathyroidism**: ↑ PTH, ↑ Ca²⁺, ↓ PO₄³⁻ • **Secondary Hyperparathyroidism**: ↑ PTH, ↓ Ca²⁺, ↑ PO₄³⁻ • **Hypoparathyroidism**: ↓ PTH, ↓ Ca²⁺, ↑ PO₄³⁻ • **Pseudohypoparathyroidism**: ↑ PTH, ↓ Ca²⁺, ↑ PO₄³⁻ (End-organ resistance)