Multiple Endocrine Neoplasia — Flashcards

Flashcard 1: The most common cause of primary hyperaldosteronism is _____

Answer: Bilateral adrenal hyperplasia (idiopathic hyperaldosteronism)

Flashcard 2: _____ HPT is hyperparathyroidism and hypercalcemia occuring after 6 month period of documented normocalcemia

Answer: Recurrent

Flashcard 3: What is the most common manifestation of MEN1 syndrome?_____

Answer: Primary hyperparathyroidism

Flashcard 4: Most common cause of primary hyperparathyroidism is a _____

Answer: adenoma

Flashcard 5: Secondary sexual characteristics are normal in _____ and Androgen Insensitivity Syndrome (AIS).

Answer: Müllerian agenesis (MRKH)

Flashcard 6: Summary of laboratory findings in parathyroid diseases (PTH, Calcium, Phosphate)

Answer: See table for Primary/Secondary/Tertiary Hyperparathyroidism, Hypoparathyroidism, and Pseudohypoparathyroidism.

Extra: • **Primary Hyperparathyroidism**: ↑ PTH, ↑ Ca²⁺, ↓ PO₄³⁻ • **Secondary Hyperparathyroidism**: ↑ PTH, ↓ Ca²⁺, ↑ PO₄³⁻ • **Hypoparathyroidism**: ↓ PTH, ↓ Ca²⁺, ↑ PO₄³⁻ • **Pseudohypoparathyroidism**: ↑ PTH, ↓ Ca²⁺, ↑ PO₄³⁻ (End-organ resistance)

Flashcard 7: 1. Identify → _____ 2. Use → _____

Answer: Insulin Syringe

Extra: y

Flashcard 8: A defective androgen receptor presents with _____ testosterone and increased LH

Answer: increased

Flashcard 9: _____ diabetes insipidus is characterized by polyuria and polydipsia with an inability to concentrate urine due to lack of ADH

Answer: Central

Flashcard 10: _____ is the most common cause of isolated elevated alkaline phosphatase in patients > 40 years old

Answer: Paget disease of bone