Endocrinology — Flashcards

Flashcard 91: _____ syndrome, or primary hyperaldosteronism, is caused by an aldosterone-secreting tumor

Answer: Conn

Flashcard 92: One clinical feature of Cushing syndrome is _____, which is a result of decreased osteoblast activity

Answer: osteoporosis

Flashcard 93: _____ adrenal insufficiency presents with low cortisol and high ACTH

Answer: Primary

Flashcard 94: Growth hormone cell adenoma may be diagnosed by elevated serum levels of _____ and/or IGF-1

Answer: growth hormone

Flashcard 95: Addison disease may present with decreased _____ and libido in females due to decreased levels of androgens

Answer: pubic/axillary hair

Flashcard 96: _____ is characterised by hypocalcemia and hyperphosphatemia due to resistance of PTH ONLY at the level of proximal convoluted tubule

Answer: Pseudohypoparathyroidism type 1b

Flashcard 97: Adrenal insufficiency may present with _____ and/or salt cravings due to decreased levels of glucocorticoids +/- mineralocorticoids

Answer: sugar

Flashcard 98: Classical form of 21-hydroxylase deficiency can be either _____ or simple-virilizing type

Answer: salt-wasting

Flashcard 99: One possible cause of hypopituitarism is a _____, which is a sudden hemorrhage of the pituitary gland, often in the presence of an existing adenoma

Answer: pituitary apoplexy

Flashcard 100: _____ is a hormone that may be used to treat Prader-Willi syndrome, a genetic disorder associated with growth failure, obesity, and carbohydrate intolerance

Answer: Growth hormone

Extra: Prader-Willi syndrome is a genetic disorder caused by a loss of function of specific genes on the paternal chromosome 15 (most commonly via 15q11-q13 deletion or maternal uniparental disomy).