Endocrine drugs (insulin, thyroid medications) US Medical PG Flashcards - Medical Study Cards
Master Endocrine drugs (insulin, thyroid medications) with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Endocrine drugs (insulin, thyroid medications) Flashcard Deck - 17 Cards
Flashcard 1: mestranol
Answer: estrogen
Extra: hypognadism, ovarian failure, menstrual abnormalities, HRT in postmenopausal women, androgen-dependent prostate cancer estrogen receptor-positive breast cancer, hx DVT binds estrogen receptor increased risk of endometrial cancer, vaginal bleeding in postmenopausal women
Flashcard 2: clompihene
Answer: SERM
Extra: infertility and PCOS partial agonist at estrogen receptor, prevents feedback inhibition hot flashes, ovarian enlargement, multiple pregnancy, visual disturbances
Flashcard 3: tamoxifen
Answer: SERM
Extra: ER-positive breast cancer antagonist at estrogen receptor; specific for breast tissue
Flashcard 4: raloxifene
Answer: SERM
Extra: osteoporosis (reduces bone resorption) agonist at estrogen receptor; specific to bone
Flashcard 5: progestins
Answer:
Extra: contraception, endometrial cancer, abnormal uterine bleeding binds progesterone receptor; reduces proliferation of endometrium, thickens cervical mucus
Flashcard 6: mifepristone (RU-486)
Answer:
Extra: abortion; administered with misoprostol competitive inhibitor at progesterone receptor heavy bleeding, abdominal pain
Flashcard 7: danazol
Answer: androgen
Extra: endometriosis, hereditary angioedema partial agonist at androgen receptor weight gain, edema, acne, hirsutism, masculinization, hepatotoxicity, dyslipidemia
Flashcard 8: testosterone (and methyltestosterone)
Answer: androgen
Extra: hypogonadism, anabolic stimulation after burn or severe injury masculinization in females, gonadal atrophy, premature closure of epiphyseal plates, dyslipidemia
Flashcard 9: finasteride
Answer: antiandrogen
Extra: BPH, male pattern baldness 5α-reductase inhibitor gynecomastia
Flashcard 10: flutamide
Answer: antiandrogen
Extra: prostate carcinoma nonsteroidal competitive inhibitor of testosterone receptor
Flashcard 11: spironolactone
Answer: antiandrongen
Extra: hirsutism of PCOS inhibits steroid binding gynecomastian, amenorrhea
Flashcard 12: ethinyl estradiol
Answer: estrogen
Extra: hypognadism, ovarian failure, menstrual abnormalities, HRT in postmenopausal women, androgen-dependent prostate cancer estrogen receptor-positive breast cancer, hx DVT binds estrogen receptor increased risk of endometrial cancer, vaginal bleeding in postmenopausal women
Flashcard 13: Diethylstilbestrol (DES)
Answer: estrogen
Extra: hypognadism, ovarian failure, menstrual abnormalities, HRT in postmenopausal women, androgen-dependent prostate cancer estrogen receptor-positive breast cancer, hx DVT binds estrogen receptor increased risk of endometrial cancer, vaginal bleeding in postmenopausal women, clear cell adenocarcinoma in women exposed in utero
Flashcard 14: exogenous steroid use
Answer:
Extra: increased: testosterone
decreased: LH
Flashcard 15: bromocriptine
Answer: ergot dopamine agonist
Extra: Parkinson's disease dopamine agonist
Flashcard 16: oxytocin
Answer:
Extra: paraventricular nucleus of hypothalamus posterior pituitary
Flashcard 17: vitamin A / ATRA
Answer:
Extra: measles, APML, wrinkles, acne vulgaris, keratosis pilaris pregnancy: highly teratogenic so pt must have negative pregnancy test and reliable contraception before prescription
Keywords: Endocrine drugs (insulin, thyroid medications) flashcards, medical flashcards, NEET PG preparation, USMLE Step 1 flashcards, Anki alternative, spaced repetition medical, OnCourse flashcards
