Autonomic/CV Drugs — Flashcards

Flashcard 891: In the treatment of **Cystic Fibrosis**, **pancrelipase** (Creon) is a mixture of _____ enzymes used to treat exocrine pancreatic insufficiency.

Answer: pancreatic

Extra: Pancrelipase contains lipase, amylase, and protease. It is used as pancreatic enzyme replacement therapy (PERT) when the thick mucus of CF blocks the pancreatic ducts, leading to malabsorption and steatorrhea.

Flashcard 892: Arrhythmia secondary to tricyclic antidepressants is prevented with _____

Answer: NaHCO3

Extra: Sketchy Pharmacology: Neuro/Psych

Flashcard 893: Raloxifene is primarily used to treat _____

Answer: post-menopausal osteoporosis

Flashcard 894: Phenobarbital is a barbiturate used in the acute treatment of _____ and tonic-clonic seizures

Answer: partial

Extra: Sketchy Pharmacology: Neuro/Psych

Flashcard 895: Fat-soluble vitamin deficiencies may occur with _____ intake, which can be used to treat constipation

Answer: mineral oil

Flashcard 896: Anthracyclines can target hair follicles, resulting in _____

Answer: alopecia

Flashcard 897: At which site do SGLT2 inhibitors block reabsorption of glucose? _____

Answer: Proximal tubule of the nephron

Extra: Sketchy Pharmacology: Endocrine (diabetes)

Flashcard 898: Thromboxane A2 is synthesized and released by activated platelets and causes platelet _____ and vasoconstriction

Answer: aggregation

Extra: Thromboxane A2 (TXA2) is synthesized from arachidonic acid by COX-1 in platelets. It is a potent platelet aggregator and vasoconstrictor, opposing the effects of Prostacyclin (PGI2).

Flashcard 899: _____ is a T3 hormone analog used to treat hypothyroidism and myxedema

Answer: Liothyronine

Extra: First Aid Pharmacology: Endocrine

Flashcard 900: A major adverse effect of orlistat is _____, which may lead to decreased absorption of _____

Answer: steatorrhea

Extra: First Aid Pharmacology: GI (Weight Loss)