Autonomic/CV Drugs — Flashcards

Flashcard 301: What class of anti-platelet drugs may cause TTP as an adverse effect? _____

Answer: ADP receptor inhibitors

Flashcard 302: Peripheral conversion of levodopa may cause cardiac _____

Answer: arrhythmias

Extra: Sketchy Pharmacology: Neuro/Psych

Flashcard 303: Nitroprusside promotes smooth muscle relaxation by increasing _____ (via direct release of NO)

Answer: cGMP

Extra: Sketchy Pharmacology: Cardiovascular (Antihypertensives)

Flashcard 304: _____ and _____ are D2 receptor agonists, which may be used to treat acromegaly by inhibiting secretion of GH from the anterior pituitary

Answer: Cabergoline

Extra: Sketchy Pharmacology: Thyroid, Pituitary, & Adrenal

Flashcard 305: Toxic doses of quinidine, an antiarrhythmic drug, may cause _____, which is a syndrome of tinnitus, headache, and dizziness

Answer: cinchonism

Extra: Sketchy Pharmacology: Cardiovascular (Antiarrhythmics)

Flashcard 306: Levothyroxine = _____ Liothyronine = synthetic T3

Answer: synthetic T4

Flashcard 307: Adenosine is an antiarrhythmic that is less effective in the presence of _____ and caffeine (methylxanthines)

Answer: theophylline

Extra: Sketchy Pharmacology: Cardiovascular (Antiarrhythmics)

Flashcard 308: Which anticoagulant acts **selectively** on Factor Xa (highest Xa:IIa inhibition ratio)? _____

Answer: Fondaparinux

Extra: Comparison of Factor Xa vs. Factor IIa (thrombin) inhibition: - Unfractionated Heparin (UFH): 1:1 ratio - Low Molecular Weight Heparin (LMWH): ~3:1 ratio (predominantly Xa) - **Fondaparinux**: Selective for Factor Xa (no activity against IIa)

Flashcard 309: Opioid agonists (e.g. loperamide) increase colonic phasic _____ contractions, causing increased colonic transit time

Answer: segmentation

Extra: Sketchy Pharmacology: GI (Relaxatives)

Flashcard 310: What drug class do sertraline and fluvoxamine belong to? _____

Answer: SSRIs

Extra: Sketchy Pharmacology: Neuro/Psych