Autonomic/CV Drugs — Flashcards

Flashcard 2431: _____ is a local anesthetic that may cause methemoglobinemia in toxic doses

Answer: Benzocaine

Flashcard 2432: What effect do class I antiarrhythmics have on conduction velocity of the myocardial action potential?_____

Answer: Decreased CV

Flashcard 2433: Does guaifenesin suppress the cough reflex? _____

Answer: No

Flashcard 2434: Coronary steal syndrome is the principle behind _____ stress tests

Answer: pharmacologic

Flashcard 2435: Thrombolytics are contraindicated in patients with recent _____ or head trauma

Answer: surgery

Flashcard 2436: A metabolic adverse effect of mecasermin, a recombinant IGF-1, is _____

Answer: hypoglycemia

Flashcard 2437: Which β-blocker may exacerbate vasospasm in Prinzmetal angina?

Answer: Propranolol

Flashcard 2438: Peripheral conversion of levodopa may cause _____

Answer: Nausea, vomiting, and cardiac arrhythmias (due to peripheral dopamine)

Extra: Peripheral conversion of Levodopa to Dopamine by DOPA decarboxylase (DDC) in the GI tract and periphery causes nausea, vomiting, and arrhythmias. Carbidopa is a peripheral DDC inhibitor that reduces these side effects and increases the amount of Levodopa reaching the CNS. Consequently, adding Carbidopa can worsen CNS side effects like hallucinations and dyskinesia.

Flashcard 2439: Both cimetidine and ranitidine decrease the renal excretion of _____

Answer: creatinine

Flashcard 2440: The respiratory alkalosis that occurs as a result of ascent to high altitude may be treated with _____ inhibitors

Answer: carbonic anhydrase