Autonomic/CV Drugs — Flashcards

Flashcard 2221: Do most NSAIDs reversibly or irreversibly inhibit COX-1 and COX-2?_____

Answer: Reversibly (except aspirin)

Flashcard 2222: Is thiopental used for the induction or maintenance of anesthesia?_____

Answer: Induction

Flashcard 2223: Theophylline can cause _____ (HR)

Answer: tachycardia

Flashcard 2224: Compared to benzodiazepines, nonbenzodiazepine hynotics are _____ likely to cause tolerance

Answer: less

Flashcard 2225: Digoxin is derived from the _____ plant

Answer: foxglove

Flashcard 2226: Which chronic gout drug must be administered IV?_____

Answer: Pegloticase

Flashcard 2227: What is a possible skin complication associated with amiodarone?

Answer: Blue-gray skin discoloration (hyperpigmentation)

Extra: Amiodarone is a class III antiarrhythmic. It is associated with several high-yield side effects: - **Pulmonary fibrosis** (most serious) - **Thyroid dysfunction** (hypo- or hyperthyroidism, due to its high iodine content) - **Hepatotoxicity** - **Corneal microdeposits** - **Blue-gray skin discoloration** (photodermatitis resulting in hyperpigmentation)

Flashcard 2228: What type of drug interaction is the presence of A is required for the full effects of substance B?_____

Answer: Permissive (e.g. cortisol on catecholamine responsiveness)

Flashcard 2229: Benzodiazepines can cause dose-dependent _____-grade amnesia

Answer: antero

Flashcard 2230: Class III antiarrhythmics may be used to treat _____ fibrillation (and flutter)

Answer: atrial