Autonomic/CV Drugs — Flashcards

Flashcard 2021: Senna is a _____ agent (stimulant) that acts via stimulation of the enteric nervous system and increased colonic secretions

Answer: cathartic

Flashcard 2022: Because the EGF receptor is expressed at the epidermis, patients taking Erlotinib are at risk of developing an __________ .

Answer: Acneiform rash

Flashcard 2023: The inhaled anesthetic _____ is associated with expansion of trapped gas in a body cavity as an adverse effect

Answer: N2O

Flashcard 2024: Which anticoagulant, warfarin or heparin, is used for immediate anticoagulation? _____

Answer: Heparin

Flashcard 2025: Which antacid is associated with hypophosphatemia and osteodystrophy if overused? _____

Answer: Aluminum hydroxide

Flashcard 2026: Opioid analgesics are associated with CNS _____ as an adverse effect

Answer: depression

Flashcard 2027: Cilostazol causes coronary artery vasodilation, which may result in _____ syndrome

Answer: coronary steal

Flashcard 2028: One factor that predisposes to digoxin toxicity is _____, which increases binding of digoxin to Na+-K+ ATPase

Answer: hypokalemia

Flashcard 2029: **Methotrexate** must be monitored with LFTs because chronic use increases the risk of hepatic fibrosis and _____.

Answer: cirrhosis (hepatic fibrosis)

Extra: Methotrexate is a folate antagonist (inhibits dihydrofolate reductase) used for rheumatoid arthritis, psoriasis, and certain malignancies. Chronic use is associated with hepatotoxicity, specifically the development of hepatic fibrosis and cirrhosis, which necessitates periodic monitoring of liver function tests (LFTs). It is also associated with myelosuppression and pulmonary fibrosis.

Flashcard 2030: Cardiovascular (Antiarrhythmics) _____ is a purine nucleoside with antiarrhythmic properties

Answer: Adenosine