Autonomic/CV Drugs — Flashcards

Flashcard 171: What effect do bile acid resins have on HDL levels? _____

Answer: Slightly increased

Extra: First Aid Pharmacology: Blood & Inflammation (Dyslipidemia drugs)

Flashcard 172: What class of drugs may bind to and inhibit complex I of the ETC? _____

Answer: Barbiturates

Flashcard 173: Does administering HCO3- for tricyclic antidepressant toxicity accelerate drug metabolism? _____

Answer: No - only overcomes Na channel-blocking activity

Flashcard 174: Rectal and sublingual administration have such high bioavailability because drugs will _____

Answer: bypass portal circulation*

Extra: Sublingual administration bypasses portal circulation completely by draining directly into the superior vena cava.

Flashcard 175: Which NSAID at low doses inhibits uric acid excretion? _____

Answer: Aspirin

Flashcard 176: Non-dihydropyridine CCBs are relatively contraindicated in patients with heart _____ or heart _____ due to their ability to cause cardiac depression

Answer: block

Extra: Sketchy Pharmacology: Calcium Channel Blockers (CCBs)

Flashcard 177: Thiazolidinediones (glitazones) are ligands of _____, an intranuclear receptor that regulates gene transcription

Answer: PPAR-γ

Extra: Sketchy Pharmacology: Endocrine (diabetes)

Flashcard 178: Lithium CNS toxicity can lead to slurred speech, as well as hyperreflexia and _____

Answer: seizures

Extra: #REF!

Flashcard 179: What is the route of administration of warfarin? _____

Answer: Oral

Flashcard 180: Tricyclic antidepressants antagonize the _____ histamine receptor

Answer: H1

Extra: Sketchy Pharmacology: Neuro/Psych