Autonomic/CV Drugs — Flashcards

Flashcard 1351: Hematemesis/diarrhea and shock and anion gap metabolic acidosis → hepatic necrosis / bowel obstruction = _____ poisoning

Answer: iron

Flashcard 1352: What drug class do clopidogrel, ticagrelor, and prasugrel belong to? _____

Answer: ADP (P2Y12) receptor inhibitors

Flashcard 1353: _____ is responsible for ↑ DVT risk

Answer: Estrogen

Flashcard 1354: DOC for mild IBD = _____ DOC for moderate IBD = _____ DOC for severe IBD = TNF-a inhibitor (Infliximab, for Crohn) vs. Surgery (UC) DOC for IBD flares = steroids

Answer: 5-aminosalicylates (sulfasalazine, mesalamine)

Flashcard 1355: Prior to removal of a pheochromocytoma, irreversible _____, such as phenoxybenzamine are administered, followed by _____

Answer: α-antagonists

Flashcard 1356: _____ is a condition with ↑ survival with riluzole

Answer: ALS

Flashcard 1357: Which antiplatelet medication is commonly used in the management of peripheral arterial disease (PAD) to reduce the risk of cardiovascular events? _____

Answer: Clopidogrel

Extra: Management of PAD includes lifestyle changes (smoking cessation, supervised exercise), high-intensity statins, and antiplatelet therapy (Aspirin or **Clopidogrel**). **Cilostazol** (a PDE3 inhibitor) is used specifically for symptomatic treatment of **intermittent claudication** (to improve walking distance) but does not reduce cardiovascular mortality. Note: In patients with PAD, Clopidogrel has been shown to be slightly more effective than aspirin in reducing cardiovascular events (CAPRIE trial).

Flashcard 1358: High intensity statins = _____ and _____

Answer: atorvastatin

Flashcard 1359: Which SSRI is contraindicated during pregnancy? _____

Answer: Paroxetine

Flashcard 1360: What drug class do glyburide, glimepiride, and glipizide belong to? _____

Answer: 2nd generation sulfonylureas