Autonomic/CV Drugs — Flashcards

Flashcard 1331: HER2/neu (+) breast cancer treatment and side effect? _____

Answer: Trastuzumab (herceptin); reversible cardiotoxicity

Flashcard 1332: Long-term PPI = _____ Mg and Fe and Ca

Answer: ↓

Flashcard 1333: Sulfonylureas and meglitinides may cause weight _____ as a side effect

Answer: gain

Flashcard 1334: Tamoxifen is a SERM that acts as an estrogen receptor _____ in breast and _____ in endometrium

Answer: antagonist

Flashcard 1335: Acute lithium toxicity = _____ side effects Chronic lithium toxicity = _____ side effects

Answer: GI

Flashcard 1336: "liptin" Sitagliptin, Saxagliptin, Linagliptin, Alogliptin _____

Answer: DPP-4 inhibitor

Flashcard 1337: What is used to treat the **muscle rigidity** and cramps seen in **Black Widow spider bites**? _____

Answer: IV calcium gluconate

Extra: Black widow venom (alpha-latrotoxin) triggers a massive release of acetylcholine and norepinephrine. This leads to severe muscle pain and abdominal rigidity (which can mimic an acute abdomen). While IV calcium gluconate is a classic board-exam association for treating these cramps, modern management focuses on supportive care with opioids and benzodiazepines. Antivenom is reserved for severe systemic envenomation.

Flashcard 1338: Contraindication to methylergonovine = _____ Contraindication to carboprost = _____

Answer: HTN

Flashcard 1339: Clomiphene is associated with _____ pregnancies

Answer: twin

Flashcard 1340: Natalizumab and rituximab have ↑ risk of _____

Answer: progressive multifocal leukoencephalopathy (JC virus)