Autonomic/CV Drugs — Flashcards

Flashcard 1001: Erlotinib is a(n) _____ inhibitor used to treat NSCLC and Pancreatic cancer

Answer: EGF-R

Flashcard 1002: Cyclooxygenase-2 expression is induced by _____

Answer: inflammation

Flashcard 1003: Which thyroid medications can cause agranulocytosis? _____

Answer: PTU and Methimazole

Extra: Development of fever or sore throat warrants discontinuation of the drug and immediate WBC count measurement to rule out agranulocytosis.

Flashcard 1004: Sickle cell anemia is treated with _____ and hydration

Answer: hydroxyurea

Extra: Hydroxyurea increases levels of HbF Other:

Flashcard 1005: What drug class does celecoxib belong to? _____

Answer: Selective COX-2 inhibitor

Flashcard 1006: Quinidine is an anti-arrhythmic that rarely causes immunologic reactions, resulting in _____

Answer: thrombocytopenia

Extra: Sketchy Pharmacology: Cardiovascular (Antiarrhythmics)

Flashcard 1007: What effect does a competitive antagonist have on potency? _____

Answer: Decrease (curve shifts right)

Flashcard 1008: Leukotrienes _____, _____ and _____ increase airway vascular permeability, mucus production, and bronchoconstriction (bronchospasm)

Answer: C4

Extra: Sketchy Pharmacology: Respiratory (Asthma)

Flashcard 1009: What pulmonary side effect is associated with adenosine? _____

Answer: Bronchospasm

Extra: First Aid Pharmacology: Cardiovascular (Antiarrhythmics)

Flashcard 1010: The _____-opioid receptor mediates most of the clinical and adverse effects

Answer: μ

Extra: Sketchy Pharmacology: Neuro/Psych