Autonomic/CV Drugs — Flashcards

Flashcard 91: Patients being treated with Imatinib can experience side effects of _____ retention

Answer: fluid

Flashcard 92: What adverse effect may desmopressin (DDAVP) have on sodium levels? _____

Answer: Hyponatremia

Extra: Sketchy Pharmacology: Thyroid, Pituitary, & Adrenal

Flashcard 93: Class IC antiarrhythmics have a(n) _____ binding affinity for the Na+ channel

Answer: strong

Extra: Sketchy Pharmacology: Cardiovascular (Antiarrhythmics)

Flashcard 94: What dermatologic complication is associated with phenytoin use? _____

Answer: Stevens-Johnson syndrome

Extra: Sketchy Pharmacology: Neuro/Psych Toxic epidermal necrolysis/Stevens-Johnson syndrome This 6-month-old patient presents with toxic epidermal necrolysis, the severe form of Stevens-Johnson syndrome. Smallpox vaccination can trigger toxic epidermal necrolysis. Stevens-Johnson syndrome following sulfonamide treatment Blistering of skin and epidermal detachment involving the conjunctiva are visible, resembling a superficial burn.

Flashcard 95: Bile acid resins (e.g. cholestyramine) indirectly _____ HMG CoA reductase activity and thus _____ cholesterol synthesis by the liver

Answer: increase

Extra: Sketchy Pharmacology: Blood & Inflammation (Dyslipidemia drugs)

Flashcard 96: What class of drugs inhibits the enzyme HMG CoA reductase? _____

Answer: Statins

Flashcard 97: Verapamil is a Ca2+ channel blocker that may cause hyper-_____ as an adverse effect

Answer: prolactinemia

Extra: First Aid Pharmacology: Calcium Channel Blockers (CCBs)

Flashcard 98: Oral ingestion of Ferrous Sulfate can cause _____

Answer: esophagitis

Flashcard 99: Loop diuretics induce expression of _____, which leads to synthesis of prostaglandins (e.g. PGE)

Answer: COX-2

Extra: Sketchy Pharmacology: Renal (Diuretics)

Flashcard 100: Opiate receptor activation causes _____ of K+ channels

Answer: opening

Extra: Sketchy Pharmacology: Neuro/Psych