Antimicrobials — Flashcards

Flashcard 871: Which antitumor monoclonal antibody targets CD52 of lymphocytes?_____

Answer: Alemtuzumab

Flashcard 872: How is Giardiasis treated?_____

Answer: Metronidazole

Flashcard 873: Which type of vaccine has the lowest chance of adverse reactions?_____

Answer: Subunit

Flashcard 874: Phase _____ of clinical trials is the postmarketing surveillance of patients after a treatment is approved

Answer: IV

Flashcard 875: What is the treatment for Clonorchis sinensis?_____

Answer: Praziquantel

Flashcard 876: Which kinase inhibitor can be used to treat CML due to t(9;22) of BCR-ABL?_____

Answer: imatinib

Flashcard 877: Which chemotherapeutic drug is known to cause bladder cancer?_____

Answer: Cyclophosphamide

Flashcard 878: One cause of folate deficiency is _____, such as folate antagonists

Answer: drugs

Flashcard 879: What formula is used to calculate half-life (t1/2) in first-order elimination kinetics?

Answer: t1/2 = (0.693 × Vd) / CL

Extra: Where: - Vd = Volume of Distribution - CL = Clearance - 0.693 = ln(2) In first-order kinetics, half-life is constant and independent of the drug concentration.

Flashcard 880: Which phase of the cell cycle does teniposide act at?_____

Answer: S and G2 phase