Antimicrobials — Flashcards

Flashcard 541: Which of the platinum analogs is most commonly associated with myelosuppression?

Answer: Carboplatin

Flashcard 542: Which two tyrosine kinase inhibitors are associated with hyperkeratosis and hemorrhage?_____

Answer: Sunitinib and sorafenib

Flashcard 543: In patients taking ruxolitinib, an important side effect is _____toxicity

Answer: hemato

Extra: Ruxolitinib is a JAK1/JAK2 inhibitor used in the treatment of myelofibrosis and polycythemia vera. Its primary dose-limiting side effects are **hematologic toxicities**, specifically **anemia** and **thrombocytopenia**. While mild LFT elevations can occur, "hematotoxicity" is the high-yield side effect for medical examinations.

Flashcard 544: In the setting of acute acetaminophen toxicity, _____ can be used to adsorb acetaminophen

Answer: activated charcoal

Flashcard 545: Fluoroquinolone risk of tendon and cartilage damage is increased with concurrent _____ use

Answer: corticosteroid (ie: prednisone)

Flashcard 546: What neurological side effect is associated with danazol?_____

Answer: Pseudotumor cerebri

Flashcard 547: Toxocara canis is treated with _____

Answer: albendazole

Flashcard 548: 5-fluorouracil is a prodrug that is converted to its active form _____

Answer: 5-fdUMP

Flashcard 549: Which types of vaccines usually requires booster shots?_____

Answer: Killed/inactivated vaccine

Flashcard 550: Are NSAIDs useful as anti-inflammatory agents?_____

Answer: Yes