Antimicrobials — Flashcards

Flashcard 541: Are NSAIDs useful as anti-inflammatory agents?_____

Answer: Yes

Flashcard 542: Fluoroquinolone risk of tendon and cartilage damage is increased with concurrent _____ use

Answer: corticosteroid (ie: prednisone)

Flashcard 543: In the setting of acute acetaminophen toxicity, _____ can be used to adsorb acetaminophen

Answer: activated charcoal

Flashcard 544: Which of the platinum analogs is most commonly associated with myelosuppression?

Answer: Carboplatin

Flashcard 545: In patients taking ruxolitinib, an important side effect is _____toxicity

Answer: hemato

Extra: Ruxolitinib is a JAK1/JAK2 inhibitor used in the treatment of myelofibrosis and polycythemia vera. Its primary dose-limiting side effects are **hematologic toxicities**, specifically **anemia** and **thrombocytopenia**. While mild LFT elevations can occur, "hematotoxicity" is the high-yield side effect for medical examinations.

Flashcard 546: In addition to increased ulcer healing, bismuth subsalicylate may be used to treat _____ diarrhea

Answer: Traveler's

Flashcard 547: Which chemotherapeutic drug is used in bone marrow ablation prior to marrow transplant?_____

Answer: Busulfan

Flashcard 548: Which phase of drug metabolism is lost first in geriatric patients? _____

Answer: Phase I

Flashcard 549: 5-fluorouracil is a prodrug that is converted to its active form _____

Answer: 5-fdUMP

Flashcard 550: What neurological side effect is associated with danazol?_____

Answer: Pseudotumor cerebri