Antimicrobials — Flashcards

What toxic intermediate is formed in small amounts by metabolism of acetaminophen? _____

Cladribine is a DNA polymerase inhibitor that treats _____ leukemia

Administration of methotrexate results in a build-up of _____ in cells

Trichuris trichiura (whipworm) is treated with _____

Rituximab is associated with _____ and has been known to reactivate hepatitis B

Ipilimumab and Pembrolizumab are monoclonal antibodies that work by downregulating _____ mechanisms*bonus: their respective targets:

6-mercaptopurine is bioactivated into its active metabolites via the enzyme _____

Cladribine is a cytotoxic _____ analog

Carfilzomib and Bortezomib are examples of antineoplastics that work by inhibiting the _____

Which chemotherapeutic drug is the most widely-used treatment of colorectal cancer?_____