Antimicrobials US Medical PG Flashcards - Medical Study Cards
Master Antimicrobials with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Antimicrobials Flashcard Deck - 10 Cards
Flashcard 41: Taxanes work by preventing the _____ of microtubules
Answer: disassembly
Extra:
https://onlinemeded.org?ref=anki
Flashcard 42: _____ inhibits thymidylate synthase, which catalyzes conversion of dUMP to dTMP (pyrimidine synthesis)
Answer: 5-fluorouracil (5-FU)
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/dna-structure?index=8]
https://onlinemeded.org/spa/metabolism?ref=anki
Flashcard 43: Patients who are slow _____ have increased side effects from certain drugs due to decreased rate of metabolism
Answer: acetylators
Extra:
https://onlinemeded.org?ref=anki
Flashcard 44: Topoisomerase I inhibitors are antineoplastic agents (commonly with the suffix -otecan) that work by preventing cell cycle progression at the _____ phase
Answer: S
Extra: Topoisomerase I inhibitors (irinotecan, topotecan) inhibit the religation of single-strand DNA breaks. These drugs are cell cycle-specific, acting during the S phase when DNA replication occurs.
Note: Topoisomerase II inhibitors (etoposide, teniposide) act on both the S and G2 phases.
Flashcard 45: Which commonly used disinfectant causes free radical production which oxidizes cellular components?
_____
Answer: H2O2
Extra:
https://onlinemeded.org?ref=anki
Flashcard 46: Patients typically get chronically exposed to Alkylating agents when they are being given _____
Answer: oncologic chemotherapy
Extra:
https://onlinemeded.org?ref=anki
Flashcard 47: Colchicine is primarily used for treatment of diseases that involve dysfunction of _____
Answer: neutrophils
Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/mitosis-meiosis-and-the-cell-cycle?index=2]
https://onlinemeded.org/spa/cardiology/pericardial-disease/acquire?ref=anki
Flashcard 48: Azathioprine/6MP are metabolized by the enzyme _____, thus inhibitors of that enzyme can boost serum levels of these drugs
Answer: xanthine oxidase
Extra:
https://onlinemeded.org/spa/immunology/immunosuppression/acquire?ref=anki
Flashcard 49: What drug is used to avoid marrow suppression during treatment of Toxoplasmosis?
_____
Answer: Leucovorin
Extra:
Watch Toxoplasma gondii [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-parasites/videos/medical-microbiology-parasites-protozoa-of-the-cns-toxoplasma-gondii?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/metabolism?ref=anki
Flashcard 50: Cetuximab is an antitumor monoclonal antibody that targets _____
Answer: EGFR
Extra:
Watch Rituximab, cetuximab, bevacizumab, alemtuzumab, trastuzumab [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antineoplastics/videos/medical-pharmacology-antineoplastics-kinase-inhibitors-and-monoclonal-antibodies-rituximab-cetuximab-bevacizumab-alemtuzumab-trastuzumab?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/immunology/videos/transplant-rejection?index=16]
https://onlinemeded.org?ref=anki
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