Antimicrobials — Flashcards

Taxanes work by preventing the _____ of microtubules

_____ inhibits thymidylate synthase, which catalyzes conversion of dUMP to dTMP (pyrimidine synthesis)

Which commonly used disinfectant causes free radical production which oxidizes cellular components? _____

Topoisomerase I inhibitors are antineoplastic agents (commonly with the suffix -otecan) that work by preventing cell cycle progression at the _____ phase

Patients typically get chronically exposed to Alkylating agents when they are being given _____

Patients who are slow _____ have increased side effects from certain drugs due to decreased rate of metabolism

What drug is used to avoid marrow suppression during treatment of Toxoplasmosis? _____

Colchicine is primarily used for treatment of diseases that involve dysfunction of _____

Azathioprine/6MP are metabolized by the enzyme _____, thus inhibitors of that enzyme can boost serum levels of these drugs

Dornase Alfa is an aerolized medication used in the treatment of Cystic Fibrosis that is a recombinant _____