Antimicrobials — Flashcards

Treatment of follicular lymphoma is reserved for symptomatic patients and involves low-dose chemotherapy or _____ (anti-CD20 antibody)

Hairy cell leukemia has an excellent response to _____, which is an adenosine deaminase inhibitor

Treatment of cystic fibrosis includes aerosolized _____, which hydrolyzes DNA in mucus causing decreased viscosity

What drug is used in the management of hyperuricemia in Lesch-Nyhan syndrome?_____

Hydroxyurea is useful in the treatment of sickle cell anemia because it increases levels of _____

Which antimicrobial can result in a metallic taste in mouth?_____

Hydroxyurea is indicated for use in _____ disorders (CML, polycythemia vera, etc)

Which of the alkylating agents can be used to treat glioblastoma multiforme?_____

Patients taking hydroxyurea can develop a _____ anemia

_____ inhibits the enzyme dihydroorotate dehydrogenase, which normally catalyzes the formation of orotic acid from carbamoyl phosphate and aspartate (pyrimidine synthesis)