Antimicrobials — Flashcards

Flashcard 471: Isoniazid can cause hepatotoxicity, which manifests as mild hepatic dysfunction or acute _____

Answer: hepatitis

Extra:  https://onlinemeded.org?ref=anki 

Flashcard 472: Tetanus and diphtheria = _____

Answer: toxoid vaccine (deactivated toxin)

Extra:  https://onlinemeded.org/spa/pediatrics/vaccinations/acquire?ref=anki 

Flashcard 473: For deep partial-thickness burns (i.e. 2nd-degree burns), when is silver sulfadiazine cream not indicated? _____

Answer: If burns are periorbital

Extra:  https://onlinemeded.org/spa/surgery-trauma/burns/acquire?ref=anki 

Flashcard 474: Route of administration for pentamidine in the **treatment** of *Pneumocystis jirovecii* pneumonia: _____

Answer: IV

Flashcard 475: Which burn treatment doesn't penetrate an eschar and can cause neutropenia? _____

Answer: Silver sulfadiazine

Extra:  https://onlinemeded.org/spa/surgery?ref=anki 

Flashcard 476: What is the dose-limiting side effect of hydroxyurea? _____

Answer: Myelosuppression

Extra:  https://onlinemeded.org?ref=anki 

Flashcard 477: Leflunomide inhibits _____ proliferation, which makes it especially useful for its main indication: Rheumatoid/Psoriatic Arthritis

Answer: T-cell

Extra:  https://onlinemeded.org?ref=anki 

Flashcard 478: Which antimalarial can result in retinopathy (bull's eye maculopathy)? _____

Answer: Chloroquine

Extra:  https://onlinemeded.org?ref=anki 

Flashcard 479: Hairy cell leukemia has an excellent response to _____, which is a purine analog resistant to adenosine deaminase

Answer: cladribine (2-CDA)

Flashcard 480: Treatment of cystic fibrosis includes aerosolized _____, which hydrolyzes DNA in mucus causing decreased viscosity

Answer: dornase alfa (DNase)