Antimicrobials US Medical PG Flashcards - Medical Study Cards
Master Antimicrobials with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Antimicrobials Flashcard Deck - 10 Cards
Flashcard 291: Side-effects of Dapsone include _____ and hemolytic anemia in G6PD deficiency
Answer: agranulocytosis
Extra:
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Flashcard 292: Cryptosporidium can be treated with the macrolide antibiotic _____
Answer: spiramycin
Extra:
Watch Cryptosporidium spp. [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-parasites/videos/medical-microbiology-parasites-protozoa-of-the-intestinal-tract-cryptosporidium-spp?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
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Flashcard 293: Azathioprine / 6MP can cause _____, thus must monitor liver function tests
Answer: Hepatitis
Extra:
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Flashcard 294: Which topoisomerase I inhibitor is indicated in colon cancer?
_____
Answer: irinotecan
Extra:
Watch Etoposide, teniposide, topotecan, irinotecan [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antineoplastics/videos/medical-pharmacology-antineoplastics-dna-and-cellular-division-etoposide-teniposide-topotecan-irinotecan?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
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Flashcard 295: Chimeric monoclonal antibodies can sometimes cause a(n) _____ within 7-10 days of administration
Answer: serum sickness
Extra:
Watch Rituximab, cetuximab, bevacizumab, alemtuzumab, trastuzumab [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antineoplastics/videos/medical-pharmacology-antineoplastics-kinase-inhibitors-and-monoclonal-antibodies-rituximab-cetuximab-bevacizumab-alemtuzumab-trastuzumab?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
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Flashcard 296: Ifosfamide can cause a generalized reabsorptive defect in the _____ tubule
Answer: proximal convoluted
Extra:
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Flashcard 297: Which phase of the cell cycle does topotecan act at?
_____
Answer: S and G2 phase
Extra:
Watch Etoposide, teniposide, topotecan, irinotecan [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antineoplastics/videos/medical-pharmacology-antineoplastics-dna-and-cellular-division-etoposide-teniposide-topotecan-irinotecan?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
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Flashcard 298: Which chemotherapeutic drugs form free radicals and also intercalate into DNA?
_____
Answer: Anthracyclines (doxorubicin, daunorubicin)
Extra:
Watch Bleomycin, doxorubicin, daunorubicin, actinomycin D [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antineoplastics/videos/medical-pharmacology-antineoplastics-dna-and-cellular-division-bleomycin-doxorubicin-daunorubicin-actinomycin-d?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/cardiology/videos/cardiomyopathy?index=19]
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Flashcard 299: Can Chloroquine be used to treat Plasmodium Falciparum?
_____
Answer: Yes*
Extra:
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Targets of antimalarial drugs
Illustration depicting the stages of malaria parasite within a human host
- Top left: exoerythrocytic cycle (within the liver)
- Bottom left: erythrocytic cycle (within blood)
- Right: legend of antimalarial drugs and their targets
The four main targets of antimalarial drugs are the tissue schizont, hypnozoite, blood schizont, and gametocyte, which are the asexual developmental stages of malaria parasites that occur within the liver and blood of an infected human host. Most antimalarial drugs act on the erythrocytic stages of the malaria parasite, especially the blood schizonts. Primaquin is the only antimalarial that attacks the hypnozoites, which are the dormant stages of stages of P. vivax and P. ovale, responsible for relapses of malaria.
Flashcard 300: Eribulin is a chemotherapeutic that works by inhibiting microtubule _____ and sequestering tubulin into nonfunctional aggregates
Answer: assembly
Extra:
Watch Vincristine, vinblastine, paclitaxel [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antineoplastics/videos/medical-pharmacology-antineoplastics-dna-and-cellular-division-vincristine-vinblastine-paclitaxel?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
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