Systemic Pathology US Medical PG Flashcards - Medical Study Cards
Master Systemic Pathology with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Systemic Pathology Flashcard Deck - 10 Cards
Flashcard 291: The tissue-restricted self-antigens expressed in the thymus for negative selection are due to the action of _____
Answer: autoimmune regulator (AIRE)
Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/immunology/videos/t-cells?index=2]
https://onlinemeded.org/spa/immunology?ref=anki
Flashcard 292: Polycystic kidney disease may compress the renal parenchyma and cause irreversible damage leading to _____
Answer: chronic kidney disease
Extra:
Watch Congenital & Cystic Kidney Disease [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-renal/videos/medical-pathophysiology-renal-congenital-and-chronic-kidney-disease-congenital-and-cystic-kidney-disease?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
Watch Chronic Kidney Disease (CKD) [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-renal/videos/medical-pathophysiology-renal-congenital-and-chronic-kidney-disease-chronic-kidney-disease-ckd?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/nephrology/videos/cystic-kidney-disease?index=2]
https://onlinemeded.org/spa/renal?ref=anki
Flashcard 293: PSGN may display _____ infiltrate in the mesangium and endothelium on light microscopy
Answer: leukocyte (lots of nuclei present)
Extra:
Watch Nephritic Syndrome [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-renal/videos/medical-pathophysiology-renal-glomerulopathy-nephritic-syndrome?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/nephrology/videos/nephritic-syndromes?index=2]
https://onlinemeded.org/spa/renal/nephritic-syndrome/acquire?ref=anki
Flashcard 294: Which intracranial hemorrhage more commonly causes a midline shift?
_____
Answer: Subdural hematoma
Extra:
Watch Epidural Hematoma, Subdural Hematoma, & Subarachnoid Hemorrhage [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-neuro/videos/medical-pathophysiology-neuro-cerebrovascular-epidural-hematoma-subdural-hematoma-and-subarachnoid-hemorrhage?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/neurology/videos/aneurysms-and-intracranial-hemorrhage?index=7]
https://onlinemeded.org?ref=anki
Atlas:
Flashcard 295: Psoriasis is associated with _____ thickness of the stratum granulosum
Answer: decreased
Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/dermatology/videos/inflammatory-diseases-of-the-skin?index=10]
https://onlinemeded.org/spa/musculoskeletal/inflammatory-dermatoses/acquire?ref=anki
Flashcard 296: Osteogenesis imperfecta is most commonly caused by gene defects in _____ and _____
Answer: COL1A1
Extra:
- It usually results from autosomal dominant mutations in the genes that encode the α1 and α2 chains of type I collagen
- These defects cause misfolding of the mutated collagen polypeptides, and they interfere with the proper assembly of wild-type collagen chains (a dominant negative loss of function)
Watch Congenital Bone Disorders Osteogenesis Imperfecta, Achondroplasia & Osteopetrosis [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-musculoskeletal-derm/videos/medical-pathophysiology-musculoskeletal-and-derm-bone-congenital-bone-disorders-osteogenesis-imperfecta-achondroplasia-and-osteopetrosis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org?ref=anki
Flashcard 297: What HLA subtypes are associated with Addison disease?
_____, DR3, and DR4
Answer: B8
Extra:
Watch Adrenal Insufficiency [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-endocrine/videos/medical-pathophysiology-endocrine-adrenal-disorders-adrenal-insufficiency?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/immunology?ref=anki
Flashcard 298: What HLA subtype is associated with Goodpasture syndrome?
_____
Answer: DR2
Extra:
https://onlinemeded.org/spa/renal/nephritic-syndrome/acquire?ref=anki
Flashcard 299: Fatty casts ("oval fat bodies") are often associated with the "_____" sign
Answer: Maltese cross
Extra:
Watch Nephrotic Syndrome [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-renal/videos/medical-pathophysiology-renal-glomerulopathy-nephrotic-syndrome?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/nephrology/videos/pathology-diagnostics?index=6]
https://onlinemeded.org/spa/nephrology/acute-kidney-injury/acquire?ref=anki
Step Up to Medicine:
Other:
Goljan:
Flashcard 300: Subacute granulomatous thyroiditis is thought to involve HLA-_____ polymorphisms and viral infection
Answer: B35
Extra: * HLA-B35 & viral infection -> molecular mimicry -> recognition of self antigens in the thyroid -> autoimmune destruction of thyroid.
Note: Subacute granulomatous thyroiditis is also known as De Quervain thyroiditis. It typically follows a viral upper respiratory infection and presents with a painful, tender thyroid.
Keywords: Systemic Pathology flashcards, medical flashcards, NEET PG preparation, USMLE Step 1 flashcards, Anki alternative, spaced repetition medical, OnCourse flashcards
