Breast pathology US Medical PG Flashcards - Medical Study Cards
Master Breast pathology with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Breast pathology Flashcard Deck - 10 Cards
Flashcard 1: What RBC pathology is characterized by the following Hb electrophoresis findings:90% HbS, 8% HbF, and 2% HbA2 (no HbA)_____
Answer: Sickle cell disease
Flashcard 2: Fibrocystic changes of the breast generally are _____ (malignant potential)
Answer: benign
Flashcard 3: What is the prognosis of the mucinous carcinoma subtype of invasive ductal carcinoma (breast)? _____
Answer: Good
Flashcard 4: Fibrocystic change of the breast presents as cysts with a _____ appearance on gross exam
Answer: blue-domed
Flashcard 5: What is the enzyme deficiency and accumulated substrate in Niemann-Pick disease?
Answer: Lysosomal storage disease caused by a deficiency in sphingomyelinase, leading to accumulation of sphingomyelin.
Extra: • Clinical Features: Progressive neurodegeneration, hepatosplenomegaly, and cherry-red spot on macula.
• Pathology: Foam cells (lipid-laden macrophages) are characteristic.
• Genetics: Autosomal recessive (AR).
• Population: Increased frequency in Ashkenazi Jews.
*Distinction: Unlike Tay-Sachs, Niemann-Pick presents with hepatosplenomegaly.*
Flashcard 6: Gaucher's disease
Answer:
Extra: accumulation of glucocerebrosidehepatosplenomegaly, aseptic necrosis of femur, bone crisescrumpled-paper cells
Ashkenazi JewARglucocerebrosidase
Flashcard 7: Patau's syndrome
Answer: Trisomy 13
Key features: Microphthalmia, Microcephaly, Cleft lip/palate, Polydactyly, Holoprosencephaly, and Rocker-bottom feet.
Extra: First trimester pregnancy screen:
- Decreased β-hCG
- Decreased PAPP-A
- Ultrasound: Increased nuchal translucency
Note: Most cases result in death within the first year of life.
Flashcard 8: In metachromatic leukodystrophy, sulfatides accumulate in the lysosomes of _____
Answer: oligodendrocytes
Extra:
https://onlinemeded.org/spa/metabolism?ref=anki
Atlas:
Flashcard 9: What type of cast may be seen in end-stage renal disease and chronic renal failure?
_____
Answer: Waxy casts
Extra:
Watch Chronic Kidney Disease (CKD) [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-renal/videos/medical-pathophysiology-renal-congenital-and-chronic-kidney-disease-chronic-kidney-disease-ckd?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/nephrology/videos/pathology-diagnostics?index=6]
https://onlinemeded.org/spa/nephrology/acute-kidney-injury/acquire?ref=anki
Step Up to Medicine:
Other:
Goljan:
Flashcard 10: _____ is characterized histologically by acanthosis with parakeratosis
Answer: Psoriasis
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/dermatology/videos/inflammatory-diseases-of-the-skin?index=10]
https://onlinemeded.org/spa/musculoskeletal/inflammatory-dermatoses/acquire?ref=anki
Atlas:
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