Systemic Pathology — Flashcards

Flashcard 121: Polycythemia vera is characterized by _____ RBC mass

Answer: significantly increased

Extra: Other:

Flashcard 122: Chronic gout may lead to _____ due to deposition of urate crystals in kidney tubules (urate nephropathy)

Answer: renal failure

Extra: Atlas:

Flashcard 123: DIC typically presents with _____ fibrinogen

Answer: decreased

Flashcard 124: Individuals with chronic granulomatous disease are susceptible to _____ colonization due to them both being catalase-positive organisms

Answer: Candida and Aspergillus

Extra: * Note, sketchy says ALL fungal pathogens are catalse positive

Flashcard 125: _____ syndrome is an inherited defect in type IV collagen

Answer: Alport

Extra: Atlas:

Flashcard 126: What pathology is associated with intellectual disability, prominent epicanthal folds, and a single palmar crease? _____

Answer: Down syndrome

Extra: Atlas:

Flashcard 127: Guillain-Barré syndrome can arise due to the immunologic phenomenon known as _____

Answer: molecular mimicry

Extra: * other causes include vaccination and stress Atlas:

Flashcard 128: A saddle-nose (thick) with thick cheeks is characteristic of _____ leprosy

Answer: Lepromatous

Flashcard 129: Paget disease of bone may present with "_____ facies" due to involvement of craniofacial bones

Answer: lion-like

Extra: Atlas:

Flashcard 130: Type 1 DM is caused by autoimmune destruction of β cells by _____ cells and autoantibodies produced by B cells

Answer: CD8+ T

Extra: * CD8+ killer T-cells attack pancreatic beta cells (occurs as a result of T cells losing "self-tolerance")