Systemic Pathology — Flashcards

Flashcard 111: Subperiosteal thinning may occur in the clavicles, phalanges, and skull due to elevated _____

Answer: PTH

Flashcard 112: Immunohistochemistry of glomeruli in Goodpasture syndrome shows extensive deposition of _____

Answer: complement (C3)

Flashcard 113: What vasculitis may cause interstitial restrictive lung disease? _____

Answer: Granulomatosis with polyangiitis (Wegener)

Extra: * due to necrotizing vasculitis in the lungs that produces infarctions and hemoptysis * Numerous pale, cavitating masses/lesions replace the lung tissue (elsewhere is hemorrhagic) on right

Flashcard 114: The extreme hypoxia and hypertonicity of the renal _____ may cause sickling in patients with sickle cell trait

Answer: medulla

Extra: Other:

Flashcard 115: Goodpasture syndrome is a form of RPGN that presents with a(n) _____ pattern on immunofluorescence

Answer: linear

Extra: Atlas:

Flashcard 116: Acute disseminated encephalomyelitis can be seen after infection by _____ / _____, or the rabies / small pox vaccines

Answer: chickenpox

Flashcard 117: Diffuse cortical necrosis is a renal pathology associated with _____ catastrophes and septic shock

Answer: obstetric

Flashcard 118: Congenital risk factors for cataracts include disorders of _____ metabolism

Answer: galactose

Extra: Atlas:

Flashcard 119: Hyperfiltration of the existing kidney in unilateral renal agenesis increases risk of _____ later in life

Answer: renal failure

Flashcard 120: Early renal amyloidosis affects _____, whereas later progression of renal amyloidosis affects _____

Answer: mesangium