Neoplasia — Flashcards

Flashcard 511: _____ neoplastic tumors remain localized and do not metastasize

Answer: Benign

Flashcard 512: _____ is a proliferation of clonal mature B lymphocytes with some that differentiate into monoclonal plasma cells

Answer: LymphoPlasmacytic Lymphoma (LPL)

Flashcard 513: Presence or absence of which three receptors or genes are most important in predicting response to treatment of breast cancer? _____

Answer: estrogen receptor (ER), progesterone receptor (PR) and Her2/neu amplification

Flashcard 514: Which subtype of melanoma presents with darkly pigmented nodules? _____

Answer: Nodular melanoma

Flashcard 515: What is the cancer risk associated with HPV18? _____

Answer: High

Flashcard 516: _____ carcinoma is a subtype of invasive ductal carcinoma (breast) characterized by the invasion of dermal lymphatics (often presenting as peau d'orange).

Answer: Inflammatory

Extra: Inflammatory breast cancer (IBC) is a clinical diagnosis characterized by "peau d'orange" (skin changes resembling an orange peel) due to dermal lymphatic invasion by tumor cells, which obstructs fluid drainage.

Flashcard 517: Thymoma is a neoplasm of the thymus associated with _____, SVC syndrome, pure red cell aplasia, and Good syndrome.

Answer: myasthenia gravis

Extra: Thymoma is a tumor derived from thymic epithelial cells. It is the most common tumor of the anterior mediastinum. **Associations:** 1. **Myasthenia gravis** (most common paraneoplastic association) 2. **Pure red cell aplasia** (PRCA) 3. **Good syndrome** (hypogammaglobulinemia) 4. **SVC syndrome** (due to compression by the anterior mediastinal mass)

Flashcard 518: What cell type is characteristic of a liposarcoma? _____

Answer: Lipoblast

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Flashcard 519: Renal _____ is a benign epithelial cell tumor arising from the collecting ducts

Answer: oncocytoma

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Flashcard 520: _____ nevi are raised papules, most commonly seen in adults

Answer: Intradermal

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