Neoplasia — Flashcards

Flashcard 471: The pathogenesis of primary CNS lymphoma involves _____ infection

Answer: EBV

Extra: Atlas: Other:

Flashcard 472: What is the most common benign soft tissue tumor in adults? _____

Answer: Lipoma

Extra: Atlas:

Flashcard 473: What is the most common cancer? _____

Answer: Skin cancer

Flashcard 474: What are the two single most important gene mutations associated with hereditary breast cancer? _____

Answer: BRCA1 and BRCA2

Flashcard 475: Tumor _____ is the degree of cellular differentiation and mitotic activity on histology

Answer: grade

Flashcard 476: The tumor suppressors encoded by the CDKN2A gene enforce the G1-->S restriction point by: (1) - inhibiting CDK_____/_____ (2) - relieving inhibition of P53

Answer: 4

Flashcard 477: What is the most common germ cell tumor in children (esp. male infants)? _____

Answer: Endodermal sinus (yolk sac) tumor

Flashcard 478: Opsoclonus-Myoclonus Ataxia Syndrome is a paraneoplastic syndrome associated with _____ in children

Answer: Neuroblastoma

Extra: - Opsoclonus = rapid, unpredictable, involuntary multivectorial conjugate fast eye movements; these do NOT have intersaccadic eye intervals

Flashcard 479: Kaposi sarcoma presents with violaceous lesions on the lower extremities, face (especially the _____), and _____ mucosa

Answer: nose

Flashcard 480: Which tumor suppressor gene is associated with neurofibromatosis type 1? _____

Answer: NF1