Neoplasia — Flashcards

Neoplasia — Flashcards

Neoplasia — Flashcards

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1687 flashcards— Page 48 of 169
#471

The PDGFB proto-oncogene encodes for Platelet-Derived Growth Factor, which upon binding to its receptor stimulates growth This is a(n) _____ found commonly in _____

Hint: class

#472

A follicular lymphoma due to Bcl-2 overexpression results from a(n) _____ mutation

#473

Which precursor lesion to penile SCC does not progress to invasive carcinoma? _____

#474

Tumor _____ is the degree of cellular differentiation and mitotic activity on histology

#475

Kaposi sarcoma presents with violaceous lesions on the lower extremities, face (especially the _____), and _____ mucosa

#476

The tumor suppressors encoded by the CDKN2A gene enforce the G1-->S restriction point by: (1) - inhibiting CDK_____/_____ (2) - relieving inhibition of P53

#477

What is the most common germ cell tumor in children (esp. male infants)? _____

#478

Which tumor suppressor gene is associated with neurofibromatosis type 1? _____

#479

What are the two single most important gene mutations associated with hereditary breast cancer? _____

#480

Opsoclonus-Myoclonus Ataxia Syndrome is a paraneoplastic syndrome associated with _____ in children

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