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Neoplasia — Flashcards

Neoplasia — Flashcards

Neoplasia — Flashcards

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1689 flashcards— Page 48 of 169
#471

A follicular lymphoma due to Bcl-2 overexpression results from a(n) _____ mutation

#472

Loss of p53 is seen in >_____% of cancers

#473

What is the most common cancer? _____

#474

The PDGFB proto-oncogene encodes for Platelet-Derived Growth Factor, which upon binding to its receptor stimulates growth This is a(n) _____ found commonly in _____

Hint: class

#475

Which tumor suppressor gene is associated with neurofibromatosis type 1? _____

#476

What are the two single most important gene mutations associated with hereditary breast cancer? _____

#477

The tumor suppressors encoded by the CDKN2A gene enforce the G1-->S restriction point by: (1) - inhibiting CDK_____/_____ (2) - relieving inhibition of P53

#478

Tumor _____ is the degree of cellular differentiation and mitotic activity on histology

#479

Opsoclonus-Myoclonus Ataxia Syndrome is a paraneoplastic syndrome associated with _____ in children

#480

What is the most common germ cell tumor in children (esp. male infants)? _____

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