Neoplasia US Medical PG Flashcards - Medical Study Cards
Master Neoplasia with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Neoplasia Flashcard Deck - 10 Cards
Flashcard 461: Basal cell carcinoma is associated with inactivating mutations in the _____ gene, which activates the Sonic Hedgehog pathway
Answer: Patched-1 (PTCH1)
Extra:
* activation of sonic hedgehog regulatory pathway -> unchecked cell proliferation and development of BCC
* PTCH1 = tumor suppressor gene
Watch Actinic Keratosis, Squamous Cell Carcinoma & Basal Cell Carcinoma [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-musculoskeletal-derm/videos/medical-pathophysiology-musculoskeletal-and-derm-derm-actinic-keratosis-squamous-cell-carcinoma-and-basal-cell-carcinoma?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/dermatology/videos/malignant-skin-disorders?index=2]
https://onlinemeded.org/spa/surgery-subspecialty/skin-cancer/acquire?ref=anki
Flashcard 462: Histopathology of mesothelioma will show tumor cells with numerous, long slender _____ and abundant tonofilaments
Answer: microvilli
Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/pulmonology/videos/lung-cancer?index=8]
https://onlinemeded.org?ref=anki
Flashcard 463: What is the most common route of metastasis for a thyroid follicular carcinoma?
_____
Answer: Hematogenous
Extra:
Watch Thyroid Nodules & Cancer [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-endocrine/videos/medical-pathophysiology-endocrine-thyroid-and-parathyroid-thyroid-nodules-and-cancer?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/endocrinology/thyroid/acquire?ref=anki
Atlas:
Flashcard 464: Follicular lymphoma may progress to _____ lymphoma, which presents as an enlarging lymph node
Answer: diffuse, large B-cell
Extra:
Watch Non Hodgkin Lymphoma [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-myeloid-lymphoid/videos/medical-pathophysiology-myeloid-and-lymphoid-lymphoid-and-plasma-cell-disorders-non-hodgkin-lymphoma?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/hematology-and-oncology/videos/leukemias-and-lymphomas?index=8]
https://onlinemeded.org/spa/hematology-oncology/lymphoma/acquire?ref=anki
Other:
Flashcard 465: Which carcinoma has a tendency to seed body cavities (e.g. the peritoneum)?
_____
Answer: Ovarian carcinoma
Extra: Peritoneal seeding may lead to ascites and bowel obstruction.
Flashcard 466: A follicular lymphoma due to Bcl-2 overexpression results from a(n) _____ mutation
Answer: t(14;18)
Extra:
https://onlinemeded.org?ref=anki
Flashcard 467: Inappropriate absolute polycythemia is characterized by _____ RBC mass
Answer: increased
Extra:
* increased production of RBCs -> increased hemoglobin, hematocrit, RBC count, and RBC mass
Watch Polycythemia [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-myeloid-lymphoid/videos/medical-pathophysiology-myeloid-and-lymphoid-myeloid-disorders-polycythemia?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/hematology-oncology/leukemia/acquire?ref=anki
Other:
Flashcard 468: Essential thrombocythemia is a myeloproliferative neoplasm with an increased number of _____ in the bone marrow
Answer: megakaryocytes
Extra:
* Platelets also seen on peripheral blood smear
Watch Myeloproliferative Neoplasms & Myelodysplastic Syndromes [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-myeloid-lymphoid/videos/medical-pathophysiology-myeloid-and-lymphoid-myeloid-disorders-myeloproliferative-neoplasms-and-myelodysplastic-syndromes?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/hematology-and-oncology/videos/plasma-cell-dyscrasias-and-myeloproliferative-disease?index=4]
https://onlinemeded.org/spa/heme-onc/myeloproliferative-disorders/acquire?ref=anki
Flashcard 469: What is the most common benign soft tissue tumor in adults?
_____
Answer: Lipoma
Extra:
https://onlinemeded.org/spa/general-physiology/skeletal-muscle/acquire?ref=anki
Atlas:
Flashcard 470: The pathogenesis of primary CNS lymphoma involves _____ infection
Answer: EBV
Extra:
Watch Adult CNS Tumors [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-neuro/videos/medical-pathophysiology-neuro-intracranial-hypertension-and-tumors-adult-cns-tumors?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/neurology/videos/adult-primary-brain-tumors?index=12]
https://onlinemeded.org/spa/hematology-oncology/lymphoma/acquire?ref=anki
Atlas:
Other:
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