Neoplasia US Medical PG Flashcards - Medical Study Cards
Master Neoplasia with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Neoplasia Flashcard Deck - 10 Cards
Flashcard 461: Basal cell carcinoma is associated with inactivating mutations in the _____ gene, which activates the Sonic Hedgehog pathway
Answer: Patched-1 (PTCH1)
Extra:
* activation of sonic hedgehog regulatory pathway -> unchecked cell proliferation and development of BCC
* PTCH1 = tumor suppressor gene
Watch Actinic Keratosis, Squamous Cell Carcinoma & Basal Cell Carcinoma [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-musculoskeletal-derm/videos/medical-pathophysiology-musculoskeletal-and-derm-derm-actinic-keratosis-squamous-cell-carcinoma-and-basal-cell-carcinoma?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/dermatology/videos/malignant-skin-disorders?index=2]
https://onlinemeded.org/spa/surgery-subspecialty/skin-cancer/acquire?ref=anki
Flashcard 462: What is the most common route of metastasis for a thyroid follicular carcinoma?
_____
Answer: Hematogenous
Extra:
Watch Thyroid Nodules & Cancer [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-endocrine/videos/medical-pathophysiology-endocrine-thyroid-and-parathyroid-thyroid-nodules-and-cancer?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/endocrinology/thyroid/acquire?ref=anki
Atlas:
Flashcard 463: Which carcinoma has a tendency to seed body cavities (e.g. the peritoneum)?
_____
Answer: Ovarian carcinoma
Extra: Peritoneal seeding may lead to ascites and bowel obstruction.
Flashcard 464: Tumor staging utilizes the TNM system:
T: _____
N: Spread to regional lymph nodes
M: Metastasis
Answer: Tumor size and/or depth of invasion
Extra:
https://onlinemeded.org?ref=anki
Flashcard 465: The PDGFB proto-oncogene encodes for Platelet-Derived Growth Factor, which upon binding to its receptor stimulates growth
This is a(n) _____ found commonly in _____
Answer: growth factor
Extra:
https://onlinemeded.org?ref=anki
Flashcard 466: What is the most common cancer?
_____
Answer: Skin cancer
Extra:
https://onlinemeded.org?ref=anki
Flashcard 467: A follicular lymphoma due to Bcl-2 overexpression results from a(n) _____ mutation
Answer: t(14;18)
Extra:
https://onlinemeded.org?ref=anki
Flashcard 468: Essential thrombocythemia is a myeloproliferative neoplasm with an increased number of _____ in the bone marrow
Answer: megakaryocytes
Extra:
* Platelets also seen on peripheral blood smear
Watch Myeloproliferative Neoplasms & Myelodysplastic Syndromes [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-myeloid-lymphoid/videos/medical-pathophysiology-myeloid-and-lymphoid-myeloid-disorders-myeloproliferative-neoplasms-and-myelodysplastic-syndromes?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/hematology-and-oncology/videos/plasma-cell-dyscrasias-and-myeloproliferative-disease?index=4]
https://onlinemeded.org/spa/heme-onc/myeloproliferative-disorders/acquire?ref=anki
Flashcard 469: Inappropriate absolute polycythemia is characterized by _____ RBC mass
Answer: increased
Extra:
* increased production of RBCs -> increased hemoglobin, hematocrit, RBC count, and RBC mass
Watch Polycythemia [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-myeloid-lymphoid/videos/medical-pathophysiology-myeloid-and-lymphoid-myeloid-disorders-polycythemia?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/hematology-oncology/leukemia/acquire?ref=anki
Other:
Flashcard 470: What is the most common benign soft tissue tumor in adults?
_____
Answer: Lipoma
Extra:
https://onlinemeded.org/spa/general-physiology/skeletal-muscle/acquire?ref=anki
Atlas:
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