Neoplasia — Flashcards

Flashcard 1591: The pathogenesis of primary CNS lymphoma involves _____ infection

Answer: EBV

Flashcard 1592: Ependymomas most commonly arise in the _____

Answer: 4th ventricle

Flashcard 1593: What mutation(s) are thyroid follicular carcinoma associated with?_____

Answer: RAS, PTEN, PAX8-PPARy

Flashcard 1594: Waldeyer's Ring is lymphoid tissue in the pharynx that is often involved in _____

Answer: non-hodgkin lymphoma

Flashcard 1595: Is large cell carcinoma related to smoking? _____

Answer: Yes

Flashcard 1596: Can a **Phyllodes tumor** be malignant?

Answer: Yes, some can be malignant

Extra: Phyllodes tumors are fibroepithelial tumors of the breast characterized by 'leaf-like' architecture and increased stromal cellularity. They are classified as benign, borderline, or malignant. Note: While the tumor itself can be malignant, a history of a benign Phyllodes tumor does not significantly increase the risk of developing future breast carcinomas (unlike lesions like atypical ductal hyperplasia).

Flashcard 1597: Follicular lymphoma is distinguished from reactive follicular hyperplasia by expression of _____ in follicles

Answer: Bcl2

Flashcard 1598: Do the monoblasts seen in acute monocytic leukemia typically contain myeloperoxidase (MPO)? _____

Answer: No

Flashcard 1599: What infectious pathology is associated with penile squamous cell carcinoma?_____

Answer: High-risk HPV (2/3 of cases)

Flashcard 1600: _____ of the esophagus is a malignant proliferation of squamous cells

Answer: Squamous cell carcinoma