Neoplasia — Flashcards

Flashcard 131: Meningioma is a(n) _____ tumor of arachnoid cells

Answer: benign

Extra:   Watch Adult CNS Tumors [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-neuro/videos/medical-pathophysiology-neuro-intracranial-hypertension-and-tumors-adult-cns-tumors?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org?ref=anki Atlas: 

Flashcard 132: _____ nevi are flat macules, most commonly seen in children

Answer: Junctional

Extra: Junctional nevi represent the earliest stage of melanocytic nevus development. The nests of melanocytes are confined to the dermal-epidermal junction. As they mature, they migrate into the underlying dermis to become compound nevi and eventually intradermal nevi. Watch associated Bootcamp video [https://app.bootcamp.com/med-school/dermatology/videos/additional-dermatologic-disorders?index=6]

Flashcard 133: Which tumor suppressor gene is associated with colon cancer? _____

Answer: DCC

Extra:  Watch Colorectal Polyps & Cancer [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-gi/videos/medical-pathophysiology-gi-colorectal-and-anal-disorders-colorectal-polyps-and-cancer?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=9] https://onlinemeded.org?ref=anki 

Flashcard 134: Invasive moles are diagnosed by histologic evidence of villi invading the _____ on a hysterectomy specimen

Answer: myometrium

Extra:   * seen in 15-20% of complete hydatidiform moles Watch Hydatidiform Mole & Choriocarcinoma [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-reproductive-gu/videos/medical-pathophysiology-reproductive-and-gu-gestational-disorders-hydatidiform-mole-and-choriocarcinoma?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org?ref=anki 

Flashcard 135: What demographic is associated with giant cell tumor of bone? _____

Answer: Young adults (20 - 40 years old)

Extra:   Watch Benign Bone Tumors [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-musculoskeletal-derm/videos/medical-pathophysiology-musculoskeletal-and-derm-bone-benign-bone-tumors?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/endocrine/bone-tumors/acquire?ref=anki Atlas: 

Flashcard 136: Progression of colonic adenoma to carcinoma occurs with mutations in the _____ or loss of heterozygosity in the region that encodes for SMAD 2 / 4

Answer: p53

Extra:   Watch Colorectal Polyps & Cancer [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-gi/videos/medical-pathophysiology-gi-colorectal-and-anal-disorders-colorectal-polyps-and-cancer?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/colorectal-pathology?index=9] https://onlinemeded.org/spa/gastroenterology/colon-cancer/acquire?ref=anki Atlas: 

Flashcard 137: Which type of cancer tends to metastasize via the lymphatics to regional lymph nodes? _____

Answer: Carcinomas

Flashcard 138: In invasive carcinoma, cell-cell contacts are lost by inactivation of _____

Answer: E-cadherin

Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/pathology/videos/cellular-injury-and-neoplasia?index=4] https://onlinemeded.org?ref=anki 

Flashcard 139: What is the most important factor in determining prognosis of breast cancer? _____

Answer: Metastasis

Extra:   Watch Breast Cancer [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-reproductive-gu/videos/medical-pathophysiology-reproductive-and-gu-breast-breast-cancer?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gross-anatomy/videos/thoracic-wall?index=9] https://onlinemeded.org/spa/surgery-general/breast-cancer/acquire?ref=anki  

Flashcard 140: The classic location for basal cell carcinoma is the _____ lip

Answer: upper

Extra:   Watch Actinic Keratosis, Squamous Cell Carcinoma & Basal Cell Carcinoma [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-musculoskeletal-derm/videos/medical-pathophysiology-musculoskeletal-and-derm-derm-actinic-keratosis-squamous-cell-carcinoma-and-basal-cell-carcinoma?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/dermatology/videos/malignant-skin-disorders?index=2] https://onlinemeded.org/spa/dermatology/hyperpigmentation/acquire?ref=anki Atlas: