Neoplasia — Flashcards

Flashcard 1301: A characteristic of the transformation from normal cells to dysplastic cells is that they become _____morphic

Answer: pleo

Flashcard 1302: Patients with xeroderma pigmentosum are at risk for which type(s) of skin cancer?

Answer: Basal cell carcinoma, squamous cell carcinoma, and malignant melanoma

Extra: Xeroderma pigmentosum (XP) is an autosomal recessive disorder caused by a defect in nucleotide excision repair (NER), which prevents the repair of pyrimidine dimers formed by UV radiation. This leads to a massive increase in the risk of all major UV-induced skin cancers.

Flashcard 1303: _____ is a sex cord stromal tumor that, similarly to granulosa cell tumors, may produce estrogen

Answer: Thecoma

Flashcard 1304: What is the serum tumor marker for hepatocellular carcinoma?_____

Answer: Alpha-fetoprotein, glypican-3, PIVKA

Flashcard 1305: Are the following protective factors or risk factors for surface epithelial ovarian cancer?_____- Infertility - Nulliparity- Postmenopausal hormone therapy

Answer: Risk factors

Flashcard 1306: What is the most common testicular tumor in children (< 3 years old)?_____

Answer: yolk sac (endodermal sinus) tumor

Flashcard 1307: Mycosis fungoides may spread to involve the blood, producing _____ syndrome (T-cell leukemia)

Answer: Sezary

Flashcard 1308: What is the prognosis of medulloblastoma? _____

Answer: Highly malignant (WHO Grade IV), but radiosensitive

Flashcard 1309: Do cherry hemangiomas regress?_____

Answer: No

Flashcard 1310: When performing Immunohistochemistry; TRAP can be used to identify _____

Answer: Hairy Cell Leukemia