Antimicrobials — Flashcards

Myelosuppression due to methotrexate is reversible with _____

Which anti-epileptic is eliminated via zero order kinetics? _____

Paclitaxel (taxanes) inhibits mitotic spindle breakdown, which occurs in _____ of mitosis

Anthracyclines (-rubicin) bind _____ to cause cleavage of DNA

Procarbazine is a chemotherapeutic _____ agent used to treat hodgkin lymphoma and brain tumors

Echinococcus granulosus can be treated with _____, but the more common method is surgery

What renal tubular defect may be caused by nephrotoxins/drugs (e.g. ifosfamide, cisplatin, tenofovir, expired tetracyclines)?_____

Which of the vinca alkaloids is more commonly used in Hodgkin's lymphoma?_____

Paclitaxel can result in _____-suppression

Which drug elimination is characterized by a linear curve?_____