Antimicrobials — Flashcards

Myelosuppression due to methotrexate is reversible with _____

Doxorubicin has a _____ range of chemotherapeutic uses and is commonly used in clinical practice

Which of the platinum analogs is most commonly associated with myelosuppression?_____

Imatinib specifically inhibits the Bcr-Abl fusion protein by blocking the _____ portion

Anthracyclines (-rubicin) bind _____ to cause cleavage of DNA

Procarbazine is a chemotherapeutic _____ agent used to treat hodgkin lymphoma and brain tumors

What renal tubular defect may be caused by nephrotoxins/drugs (e.g. ifosfamide, cisplatin, tenofovir, expired tetracyclines)?_____

Mycophenolate mofetil can result in _____-suppression (-cytopenias)

Which phase of the cell cycle does azathioprine act at?_____

Gemcitabine can result in _____ with increased risk for infection