Antimicrobials — Flashcards

Taxanes work by preventing the _____ of microtubules

_____ inhibits thymidylate synthase, which catalyzes conversion of dUMP to dTMP (pyrimidine synthesis)

Because _____ are a cell population that proliferate rapidly, Azathioprine / 6MP work especially well for the treatment of _____ mediated inflammatory diseases

Patients typically get chronically exposed to Alkylating agents when they are being given _____

Topoisomerase I inhibitors are antineoplastic agents (commonly with the suffix -otecan) that work by preventing cell cycle progression at the _____ and _____ phases

Which commonly used disinfectant causes free radical production which oxidizes cellular components? _____

Patients who are slow _____ have increased side effects from certain drugs due to decreased rate of metabolism

What drug is used to avoid marrow suppression during treatment of Toxoplasmosis? _____

Colchicine is primarily used for treatment of diseases that involve dysfunction of _____

Azathioprine/6MP are metabolized by the enzyme _____, thus inhibitors of that enzyme can boost serum levels of these drugs