Systemic Pathology — Flashcards

Flashcard 351: Muscle biopsies of patients with mitochondrial myopathies often show "_____" fibers

Answer: ragged red

Flashcard 352: Which zone of the liver is affected by Yellow Fever? _____

Answer: Zone II (intermediate zone)

Extra: Atlas:

Flashcard 353: Type II MPGN is associated with _____ circulating levels of C3

Answer: low

Extra: Atlas:

Flashcard 354: Tabes Dorsalis is characterized by loss of _____ due to degeneration of the dorsal roots

Answer: deep tendon reflexes (DTRs)

Flashcard 355: The _____ Coombs test adds anti-human globulin (Coombs reagent) to a sample of a patient's RBCs

Answer: direct

Extra: Other:

Flashcard 356: What MSK pathology is characterized histologically by a mosaic pattern of woven and lamellar bone? _____

Answer: Paget disease of bone

Extra: Paget, Remodeling, Mosaic, Hat: Imagine a model with a hat walking down the pageant runway, which is a mosaic. normal = straight lines, paget = mosaic, cement lines Atlas:

Flashcard 357: Mammary duct ectasia may display _____ on mammogram

Answer: radio-opacities

Flashcard 358: In β-thalassemia major, _____ tetramers precipitate and damage RBCs

Answer: α4

Extra: * excess alpha subunits precipitate due to absence of Œ≤ subunits -> inclusion bodies damage RBC membranes -> hemolysis in spleen Atlas: Other:

Flashcard 359: _____ is the result of recurrent episodes of acute pyelonephritis

Answer: Chronic pyelonephritis

Extra: Atlas:

Flashcard 360: Membranoproliferative glomerulonephritis is associated with a '_____' appearance on PAS and H&E stain

Answer: tram-track

Extra: Atlas: Other: "Tram-track" is a keyword that may appear in different pathologies (like bronchiectasis on CT). Illustration of keyword below: