Systemic Pathology — Flashcards

Flashcard 221: Hepatitis _____ infections are more likely to cause membranoproliferative glomerulonephritis (MPGN)

Answer: C

Flashcard 222: Rheumatoid arthritis is associated with _____, which are areas of fibrinoid necrosis with palisading histiocytes in the skin and visceral organs (e.g. lung)

Answer: rheumatoid nodules

Extra: Atlas:

Flashcard 223: _____ is caused by a mutation in the filaggrin gene, resulting in dry, scaly skin

Answer: Ichthyosis vulgaris

Flashcard 224: What pathology is characterized by insatiable appetite (hyperphagia), obesity, intellectual disability, and hypogonadism? _____

Answer: Prader-Willi syndrome

Extra: "Prey" and eat a lot while hypotonic on the couch

Flashcard 225: DiGeorge syndrome is characterized by _____ number of T cells

Answer: decreased

Flashcard 226: Cysts of autosomal recessive polycystic kidney disease are lined by _____ cells

Answer: cuboidal epithelial

Flashcard 227: Diffuse proliferative glomerulonephritis is characterized by a(n) _____ pattern on immunofluorescence

Answer: granular

Extra: Atlas:

Flashcard 228: Which cause of pauci-immune glomerulonephritis is associated with c-ANCA (PR3-ANCA)? _____

Answer: Wegener granulomatosis

Extra: Several features differentiate it from other forms of crescentic GN (e.g. Goodpasture syndrome), including the presence of granulomatous vasculitis, the absence of immune complexes or anti–glomerular basement membrane (GBM) antibodies, and the presence of C-ANCA

Flashcard 229: Disorders of fibrinolysis typically present with increased _____ split products

Answer: fibrinogen

Flashcard 230: DIC typically presents with _____ bleeding time

Answer: increased