Neoplasia — Flashcards

What are the two single most important gene mutations associated with hereditary breast cancer? _____

Is chronic myeloid leukemia associated with JAK2 mutations?_____

'Triple-Negative' breast cancer is negative for ER, PR, and HER2/neu and has a _____ prognosis

Which tumor suppressor gene is associated with neurofibromatosis type 2?_____

Homologous Recombination is defective in breast/ovarian cancers with _____ mutations

What inherited cancers (2) are associated with osteosarcoma? _____

What demographic (age group) is associated with giant cell tumor of bone? _____

Mutations in which tumor suppressor genes can lead to Breast, Ovarian, and Pancreatic cancers?_____

_____ is a benign tumor of skeletal muscle

Which bone tumor arises in the epiphysis of long bones?_____