Neoplasia — Flashcards

Homologous Recombination is defective in breast/ovarian cancers with _____ mutations

Is chronic myeloid leukemia associated with JAK2 mutations?_____

'Triple-Negative' breast cancer is negative for ER, PR, and HER2/neu and has a _____ prognosis

Which tumor suppressor gene is associated with neurofibromatosis type 2?_____

What are the two single most important gene mutations associated with hereditary breast cancer? _____

_____ is a benign tumor of skeletal muscle

The peak incidence for secondary osteosarcoma is in _____

Giant cell tumor is a bone tumor comprised of multinucleated giant cells and stromal cells that express _____

What cancer has a higher incidence in patients with paroxysmal nocturnal hemoglobinuria? _____

Which bone tumor is characterized by small, round blue cells that resemble lymphocytes? _____