Neoplasia — Flashcards

Flashcard 681: What does **Mixed Cellularity** Hodgkin Lymphoma display on histology? _____ (no fibrous septa)

Answer: Diffuse infiltrate

Extra: Mixed cellularity Hodgkin lymphoma (MCHL) is characterized by a diffuse infiltrate and a pleomorphic inflammatory background (eosinophils, plasma cells, histiocytes). Unlike Nodular Sclerosis HL, it lacks fibrous bands. RS cells are usually frequent.

Flashcard 682: Mutations that cause overexpression of the HER2 receptor can precipitate development of certain Breast* and Gastric* Cancers by _____ the signal transduction

Answer: amplifying

Flashcard 683: Lymphoma is divided into _____ (60%) and _____ lymphoma (40%) *bonus: age groups

Answer: non-Hodgkin

Extra: Other:

Flashcard 684: Solitary plasmacytoma most commonly affects bone and causes _____

Answer: pain or pathologic fractures

Flashcard 685: Laryngeal carcinoma can rarely arise from a laryngeal _____

Answer: papilloma

Flashcard 686: The most common type of metastases to the bone from Small Cell Lung Cancer are _____

Answer: blastic

Flashcard 687: What is the most common somatic malignancy stemming from a cystic teratoma? _____

Answer: Squamous cell carcinoma of skin

Flashcard 688: A translocation of _____ from chromosome 11 to 14 results in overexpression and ultimately Mantle cell lymphoma

Answer: cyclin D1

Flashcard 689: _____ are rough, hyperkeratotic papules that appear on the skin due to HPV infection of keratinocytes

Answer: Verrucae (warts)

Extra: HPV types 1, 2, and 4 are most commonly associated with **verruca vulgaris** (common warts). HPV types 6 and 11 are associated with **condyloma acuminatum** (genital warts).

Flashcard 690: Foods containing N-nitroso compounds increase the risk for esophageal _____

Answer: squamous cell carcinoma